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The performative deletion analysis approach, does not assume the presence of speakers, hearers, and verbs, but rather the presence of the words "I", "you", and performative verbs. In the approach of conversational postulates, it is also possible to formalize principles of conversation and show that there are rules in grammar that are dependent on such principles. But according to John Searle, both approaches to the performative deletion analysis and the conversational postulates show a misunderstanding of the place of theory of speech acts in the general narrative of language. Searle's objection to these two approaches is that they both fail to use the sources of current theories of speech acts. Both theories, when confronted with confusing data, assume a solution that requires the introduction of additional and unnecessary components. In each, a correct understanding of the role of speech acts enables us to justify this data without providing these additional and unnecessary components.

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The purpose of this paper is to investigate the relationship between the quality of empowering the staff of Ministry of Finance and Economic Affair headquarter and the standard model of Investing in People. The research population of this study includes staffs of the headquarters of the Ministry of Finance with bachelor degree or higher who are 821 people and selected samples are 256 persons whom were chosen by Morgan’s table. Questionnaire used in this study are Spreitzer Psychological Empowerment standard questionnaire and a questionnaire which was designed according to the standard criteria of investing in people. First, the current status of psychological empowerment headquarters of the Ministry of Finance and Economic Affairs is measured and then the research hypotheses are tested and assessed by SPSS software and LISREL. Surveying the status of employee empowerment indicates the average level of empowerment in the organization and shows the need for improvements. Results also denote that there is a significant positive correlation between the quality of empowering the staff and the two components of commitment and planning. However, there is no relationship between two components of action and assessment of the standard model of Investing in People and the final model is obtained by the software.          

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Background: Many comprehensive epidemiological studies have been done about fungal infections, which areone of the publichealth and therapeutic problemsin different communities. Since prevalence rate of fungal diseases and their etiological agents are changing over time,the aim of this study was to provide additional information about visceral fungal infections (VFIs) in order to understand the ways of their dissemination, to prevent disease transmission, to eliminate contamination sources and predisposing factors, and to provide effective ways for their treatment.
Materials and Methods: Samples were taken from the lesion of patients referred to medical mycology laboratory of Tehran University of Medical Sciences from 2014 to 2015. After providing direct wet mount of Potassium hydroxide (KOH) smears from these samples and samples sent from other medical centers, culturing on Sabouraud Dextrose agar with chloramphenicol (SC) and brain heart infusion agar (BHI) media was performed. After growth, species were identified.
Results: From a total of 295 suspected samples, VFI was proved in 69 cases (23%). Aspergillosis was the most prevalent infection among VFIs. Candidiasis, cryptococcosis and mucormycosis were in the late orders, respectively. Two patients were also infected by Trichosporon. The predominant species in aspergillosis infections was Aspergillus flavus, and the predominant species in candidiasis infections was Candida albicans.
Conclusion: According to the obtained results on the prevalence rate and incidence of VFIs between male and female patients in different age groups and also by taking into account the prevalent type of fungi and infectious site of patients’ bodies, it is possible to take appropriate action for the prevention and treatment of these kinds of diseases by using the important keys of these results to research and study etiological and underlying factors involved in these diseases.

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Background: Many studies have been conducted on fungal infections which are known as public health and therapeutic problems. Since the prevalence rate of the fungal diseases and their etiological factors are changing over time, the purpose of this study was to identify the prevalence rate of superficial-cutaneous fungal infections (SCFIs) in order to understand the ways of their dissemination, to prevent diseases transmission, to eliminate contamination sources and predisposing factors, and to take appropriate action for their treatment.
Materials and Methods: After referral to medical mycology laboratory of Tehran University of Medical Science from 2014 to 2015, the patients were subjected to mycological examinations, and sampling of patients’ lesions was performed. Directsmears were prepared with Potassium hydroxide. Samples were cultured on Sabouraud dextrose agar medium, and species were identified.
Results: From a total of 916 suspected patients, 334 cases (36.5%) had SCFIs. Dermatophytosis was the most prevalent SCFI (55.7%), followed by cutaneous candidiasis (19%), tinea versicolor (14.3%), and non-dermatophytic molds (11%).Tineapedis was the frequent site of involvement. Trichophytonmentagrophytes was the predominant species of dermatophytosis.
Conclusion: According to the obtained results on the prevalence rate of SCFIs between male and female patients in different age groups and also by taking into account the type of the prevalent fungi and the involvement site of the fungal infection, it is possible to take appropriate action for prevention and treatment of these kind of diseases by using important keys of the results to research etiological and underlying factors involved in these diseases.

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In Speech Acts, John Searle dealt with the analysis of literal meaningful utterances, but in Expression and Meaning, he generalizes his theory to meaning and uses it to account for performing and understanding nonliteral utterances where the speaker means something other than what he is saying. Thus, Searle’s question about indirect speech acts is how a speaker might say something and mean it, but he also means something else. For this purpose, the area of directives is the most useful to Searle. The presence of decency in acts in the category of directive is Searle’s main motivation for researching indirect speech acts. Still, most examples are found in the acts in the category of commissive and not in the acts in the category of directive. At the same time, Searle’s approach does not conform to the usual explanatory paradigms; it’s somewhat like an epistemological analysis of perception. Thus, this article aims to review, analyze, and critique Searle’s approach.

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Background: Adverse effects of synthetic pigments used in pharmaceutical andfoodindustriesand etc,have created a tendency toward the application of natural pigments. Environmental conditions are important factors in the growth and physiological function of different organisms. The aim of this study was to evaluate the growth rate of fungal biomass and production rate of black pigment (melanin) in fungus Exophialacrusticola under different incubation time, temperature, and light conditions to obtain an optimal condition for their production.
Materials and Methods: After obtaining an optimal incubation temperature, cultured fungus in potato dextrose agar and broth media was exposed to blue, yellow, white, red, green, and darknesslight conditions with 14-35 daysof incubation times. The averageamount of produceddry weight of fungal biomass and pigmentweremeasured, and the results were statistically analyzed with SPSS software ver.22.
Results:Suitable incubation temperature for fungal growthwas 22°C.The maximum average amount of fungal biomass (0.17 g)and pigment production (OD = 0.94) were after 35 days of incubation (p< .05) and under yellow light (0.135 g) (OD= 0.98), respectively (p< .05).
Conclusion: By optimization the incubation time, temperature, and light for the growth and production of pigmentinfungusE.crusticola, it is possible to produce a large amount of fungus and its related pigmentin order to be utilized in a variety of industrialand pharmaceutical use, and etc. Also, due to the fungus rapid growth in response to the yellow light, it is possible to use this feature in isolation and early diagnosis of this fungusin suspected pathogenesiscases.

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Background:Survival of dermatophytesinskin scales and nail scraps sampled from human lesions could have ecological and epidemiologicalimportance.The aim of this study was to store humanskin scale and nail lesions infected with dermatophyteagents,at -20°C for a long timeand to investigate the re-isolation rate of dermatophytes species from such samples after storage.
Materials and Methods:After referral to Medical Mycology Laboratory of Tehran University of Medical Science, the patients were subjected to sampling. Confirmation of dermatophytepositive result in direct smears was done with Potassium hydroxide, then culturing on Sabouraud dextrose agar media was performed, and species were identifiedusing standard procedures, and remaining samples were stored at -20°C. After 10 years, samples were re-examined for the presence and re-isolation of intended fungi according to the standard procedures.
Results:From a total of 5 species enrolled in this study, Epidermophyton floccosum, Trichophyton mentagrophytes, andTricholosporumviolaceum survived, andTrichophyton rubrum andTrichophytonverrucosumlost their viability at -20°C after 10 years. There was a significant difference between the re-isolation rate and the type of dermatophytes (p<.05). E. floccosum had the highest re-isolation rate (66.7%), followed by T. mentagrophytes (27%). All of the re-isolated dermatophytes were taken from scales samples, but none from nailscraps samples.
Conclusion: Some dermatophytes species including E. floccosum are able to maintain their ability to survive for a long time in human scale samples in certain time and temperature conditions (10 years at -20 °C) and to grow in appropriate conditions. These findings should be considered in ecological and epidemiological studies.

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The effect of simultaneous application of probiotic and digestive enzyme on the intestinal digestive activity of the whiteleg shrimp, Litopenaeus vannamei, was evaluated. For this purpose, the juvenile shrimps were fed for 30 days with a dietary probio-enzyme (containing a combination of six exogenous enzymes and four probiotic bacterial strains) at four concentrations of 0, 0.25, 0.5, and 1 g kg^-1 feed. Shrimps (5.04±0.39 g ind^-1) were randomly distributed in 12 aquaria (4 treatments × 3 replications); each aquarium contained 15 individual shrimps. Results indicated significantly (p≤0.05) higher growth performance, amylase and lipase activity at 0.5 g kg^-1 treatment as compared to other treatments. Protease activity was, however, significantly (p≤ 0.05) higher at 1.0 g kg^-1treatment as compared to other groups. Results also indicated that increase in the concentration of probiotic and enzymes supplementation was not associated with increase in all the digestive enzyme activity. In other words, probiotics and enzymes onlywithin specific range can have positive effect on growth performance and digestive enzyme activity of L. vannamei, above or below.

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The purpose of this study is to analyze the challenges of political marketing with the approach of using the soft power of the Islamic Republic of Iran. Categories related to each of them were extracted using content analysis method and these 6 groups were ranked using Friedman test by SPSS26 software. According to the results, the highest ranking was given to the techniques used in international political marketing with the approach of diplomacy, media power, ideological power, cultural power, economic power and management system power. Persuasion and third place became the most prominent dimension of international political marketing, namely national identity. Iran's current position in terms of identity, international prestige and economic identity ranks fourth, restrictions on the use of political marketing ranks fifth with unique ideological approach, financial challenges and theoretical poverty and the most effective Iranian foreign policy discourse ranks sixth with de-escalation and balance discourse approach. Finally, the analytical model of political marketing affected by limitations, necessities and the most significant dimension using effective techniques and the best discourse in promoting Iran's current position in the economic field and strengthening the international image are presented. Practical suggestions are also provided based on research questions for the Ministry of Foreign Affairs, the Economic Deputy of this agency and non-governmental organizations including the Red Crescent and other responsible agencies and organizations.

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Energy efficiency and comfort consideration in building, contribute to significant energy saving and improvement of spatial quality. According to the importance of energy issues and lack of researches on energy use in educational buildings, climatic variation in the country and huge amount of energy consumption in educational buildings, the need of redefinition environmental design criteria is essential.
The main purpose of this article is to assess the influence of different design variables on comfort condition and energy consumption in the hot-Arid climate of Tehran. Most of the literature concerned with energy performance of school buildings is focused on using saving methods such as utilization of solar energy, constructional issues such as thermal insulation, infiltration, thermal mass, building materials, sun shadings and HVAC performance while assuring thermal comfort and indoor air quality of the building. However, the topic of energy performance and comfort condition of schools located in Iran’s climatic conditions has not been explored.
Nowadays, the subject of energy and optimizing energy consumption in different buildings and different societies is of great importance. On the other hand, energy experts claim that in designing educational buildings, natural energy resources should be used most. This subject is related to the energy consumption of schools. Furthermore, the positive effect of thermal and visual comfort on the quality of students’ education has been confirmed. Educational buildings generally are spaces with different functions.
However, classrooms not only have a central role, but also cover a great part of the school surface. Classrooms are the most fundamental and important units of the educational buildings in terms of energy consumption and thermal comfort. Students spend most of their time in the classrooms. Classrooms are more important, given the relative congestion in comparison with other educational spaces. Due to this fact, proper ventilation is considered necessary. Furthermore, students’ presence as latent thermal energy sources needs special attention in hot seasons. On the other hand, the same thermal sources can play an effective role in creating the comfortable conditions. Therefore, according to the difference of using pattern of these places and their higher internal heat gain, energy saving patterns in designing office and residential buildings cannot meet the needs of designing these buildings.
Methodology
This research using simulation method is looking forward to realize the influence of different physical variables on energy consumption in educational buildings in Tehran’s climate; the different circumstances that were resumed by diverse variables were assayed. this process took place with the help of E quest energy simulating software and during this process in two separate parts, the independent effect of each variable and the simultaneous influence of applying diverse variables on energy consumption were simulated and its results were compared and discussed in various steps.to enumerate the most essential effective parameters in determining the amount of energy consumption in educational building in Tehran’s climate, we can point out the infiltration rate, heat isolating of the building roof and windows dimension.
To understand the range of influence of each variable on the comfort condition and energy consumption in the classroom, the difference between the maximum and minimum energy consumption obtained for each of the evaluated variables was considered. This difference represents the potential savings that can be achieved by improving a variable within the considered range of values. In this work, the four main orientations were analyzed.to observer the influence of design parameters on energy consumption, a base case classroom was designed and then the absolute and simultaneous effects of different parameters were assessed. The base-case was a common classroom to where all changes were applied and examined. Based on the similar studies, the recommended value for each design variable was determined to achieve a high
performance classroom. The fixed parameters of the classroom were its size and height. The thermostat of the heating system was set at 21.1 C while the thermostat of the cooling system was set at 24 C, due to the dissimilarity in the children’s clothing in different seasons. The ventilation system provides a minimum of 4.5 air changes-per-hour (ach) when the classroom is occupied. When there were no children in theclassroom, the ventilation rate will reduce to save energy and the lighting level on the children’s tables was set at a minimum of 300 lux.
Results
The results indicate that by reducing the infiltration rate of the classroom from 4.5 ACH to 0.75 ACH, an energy saving of about 65 KWH/m2.y will achieved. The airtightness of a classroom depends on windows and doors type, quality, and materials as well as on the quality of the construction process. For obtaining infiltration rate of about 0.75 ACH, designers and contractors should give more attention to the quality control of materials and construction and energy performance of the windows and the doors. Meanwhile according to the high amount of sun radiation during the year, roof heat insulation with a 6cm polyurethane layer would reduce the energy consumption by 40 KWH / m2.y in comparison with a roof without any heat insulation. Since the windows have a significant influence on the energy consumption and performance of the classroom, In order to reduce the energy consumption, dimensions and position of the windows should be choose very carefully. It was observed that the recommended size of north and south facing windows is equal to %12 of the classrooms floor area, whilst east and west facing windows should not be exceeds from %10 of the classroom area. If the windows size exceed from %12 of floor area, the glare effect would make visual discomfort for the students. In the simulation process, three types of light control features were evaluated. The results show that with the aid of smart lighting control system, the required electrical energy for lighting would reduce 34 KWH / m2.y. And finally the types of glazing have an important role in energy consumption of the classroom. It is observed that high performance was achieved when using lowemissivity
glazing to reduce cooling loads and encourage daylight in classroom. Double glazed windows shows acceptable performance as well, in all directions compared to other alternatives.
Discussion and Conclusion
After analyzing the absolute effect of each parameters on energy consumption and comfort condition in the classroom, the cumulative effect of all parameters were analyzed. It is obvious that by changing of each parameter, the effect of other parameters will be changed. In this case two combination of design variables are assessed in “set-a” and “set-b” in which the annual energy consumption of the classroom is maximum in “set- a” and minimum in “set-b”. Based on the results obtained by simulation, this can be claimed that the proper design of classrooms in hot and arid climate, like the city of Tehran can reduce the amount of energy required for cooling, heating, ventilating and lighting systems from 232 KWH/ m2.y in “set-a” to 104 KWH/ m2.y in “set- b”. It means a %55 reduction in the classroom’s energy consumption. This statics are in conformity with the results achieved by researches in European’s green school which can reduce %55 up to %75 of heating energy consumption and 30 % up to 40 % of electrical energy consumption by using different tricks.

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Aluminum alloys have high strength to weight ratio and Poor formability at room temperature is the main drawback of using these alloys. In order to overcome this limitation, the work material is formed at higher temperature. One of the forming processes is hydrodynamic deep drawing on which no relevant research has been reported in warm condition. In the present paper, after examining the formability of 5052 aluminum alloy in warm hydrodynamic deep drawing, the effect of media pressure, temperature and forming speed on thickness distribution and punch force in forming of flat-bottom cylindrical cups was investigated. In order to perform a complete investigation, the simulation of the process was established using ABAQUS software. It was illustrated that the results was in accordance with the experimental findings. It was also demonstrated that increasing the maximum oil pressure to a specified level could improve the thickness distribution and lead to increasing the punch force. The required punch force was decreased with increase in temperature but remained unchanged by punch speed variation. The maximum thickness reduction was decreased with increasing and decreasing of temperature and punch speed, respectively. Moreover, the forming of the sheet at room temperature, isothermal and non-isothermal warm forming processes was compared. It was concluded that the maximum thickness reduction in the formed part was less in the cases of cold forming and non-isothermal warm forming than the isothermal warm forming. But the required forming force is decreased in isothermal warm forming when compared with the other two conditions.

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Baluchi sheep is considered as the most common breed in Iran, constituting about 30% of total sheep population, approximately 15 million heads. This research was designed to study the incidence of mutation in two loci of IGF-I (Exon 3) and ADRB3 (Intron) along with their association with body weight traits in Baluchi sheep population. Following DNA extraction from 190 Baluchi sheep, two pairs of primers were designed to amplify each gene. PCR-SSCP (Single-Strand Conformation Polymorphism) and DNA sequencing were employed to detect polymorphism of the mentioned genes. Two banding patterns were detected for IGF-I locus. The frequencies of AA, AB were recorded as 0.89, 0.11, respectively in IGF-I locus. As for ADRB3, two patterns corresponding with two genotypes (their frequencies mentioned in parentheses) of AA (0.85) and AB (0.15) were identified. One SNP change was observed in ADRB3, and one in IGF-I. A previously reported SNP was detected in exon 3 of IGF-I. The effects of IGF-I and ADRB3 polymorphism on the corrected phenotypes for body weight at birth (BW), weaning (WW), 6 months of age (6MW), 9 months of age (9MW) and 12 months of age or Yearling Weight (YW) were examined using least square methods. No significant association was detected between the polymorphism of IGF-I and body weights. As for ADRB3, the genotype AA was found out to exert a significant positive effect on 6MW (AA, 30.20±1.85 kg day^-1; AB, 27.67±1.98 kg day^-1; P<0.05).

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This paper deals with the problem of safe grasping of an object. According to robot maneuvers during of movement, the slipping or falling of the objects is possible. Here, an adaptive backstepping control method is used for controlling of slipping and tracking of desirable paths. First, the robot dynamics of grasping of an object including mechanical arm with three rotational joints, one prismatic joint, jaw gripper as well as dynamic of the electrical actuators is derived. Then, backstepping technique, which is a systematic approach based on Lyaponov theory, is applied for this nonlinear system. Beacuse of existence of different uncertainties in this system such as mass and inertia of robot and object mass, it is required to design a controller to be able to cope with these uncertainties. Accordingly, a stable controller using adaptive backstepping control methodology is also designed to estimate of these parameters’ uncertainties. Stability analysis is provided based on Lyapunov theory. Simulations are carried out to evaluate the performance of the proposed controller. Results show the effectiveness of the proposed control method.

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In this paper, a practical method of combined finite element simulation and adaptive simulated annealing (ASA) optimization was developed to design and analyze sheet hydroforming process. Process simulation using finite element code with parametric definition of process parameters creates flexibility on the proposed method in which geometrical dimensions and properties of the workpiece and the die comprise a part of input data of optimization program. Redefinition of simulated annealing parameters with respect to hydroforming process caused to achieve data convergence in a shorter time and higher precision. An intermediate MATLAB code was developed to manage data transfer automatically between optimization and simulation codes, in which there would be no need to any interference of user/designer during the optimization process. The aim of this research for presenting the combinatorial procedure of flexible simulation is to achieve optimal forming pressure loading path, determine the desired punch velocity, produce the desired workpiece with minimum thinning, and avoid wrinkling and rupturing. Two different loading paths proportionate to the ram’s stroke of press unit are proposed to synchronize optimal pressure path and desired punch velocity in forming of cup-shaped products. Using the optimization approaches of constant and variable velocity, thinning values of 12.9778 and 12.3295 for a steel part with conical shape were obtained by implementing simulation iteration of 202 and 148, respectively. This result demonstrates improvement of product quality and decrease of simulation iterations in variable velocity. Appropriate conformity between numerical and experimental results verified the reliability and accuracy of the proposed optimization method.

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Today, with the development of technology, industries such as automotive and construction require products with variable cross section. Multiplicity of steps, dimensional limitation and high production costs of the components caused flexible roll forming process used to produce these products. One of the main defects in this process is the fracture phenomenon. The fracture is observed on the bending edges at transition zone that sheet thickness is large compared to the bending radius. In this research the fracture phenomenon is investigated on flexible roll forming process of channel section using ductile fracture criteria. For this purpose finite element simulation of the process using Abaqus software is done. The fracture defect in this process is investigated using six ductile fracture criteria by developing a subroutine. Experimental tests are performed on 27 specimens precut sheet of AL6061-T6, using flexible roll forming machine built in Shahid Rajaee University. By comparing simulation results with experimental results, numerical results were validated. In addition, by comparing the results of ductile fracture criteria with experimental results, the Argon ductile fracture criteria, was chosen as the most appropriate criterion to predict fracture. Also the effects of parameters as sheet thickness, bending radius and bending angle on fracture with argon selected criterion is studied.

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Abstract
Free radicals cause many diseases in human. Antioxidants reduce the risk of cardiovascular disease and stroke by neutralizing free radicals and on the other hand, prevent progression of cancer. The natural antioxidant enhances antioxidant properties of plasma to prevent diseases such as heart disease, cancer, and stroke. Plants are a rich source of secondary compounds, which are the most important natural antioxidants.
In this study, Fumaria vaillanti aqueous, methanol and ethanol extracts were used to determine the anticancer effect of extracts on Breast Cancer Cells Lines BT-474, MDA-MB_231 after 24, 48 and 72h.
The highest percentage of cell death, according to the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) technique, has been reported in the aqueous extract on MDA-MB-231 cells after 72 hours at with IC₅₀ of 2 μg / ml.
The results of this study indicate that Fumaria vaillanti shows a significant antioxidant and cell toxicity effect and full potential of extracts can be realized by further studies on animal models and subsequent trials.