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Background: Parasitic infections can cause different chemical changes in human body. This study was designed to determine the liver aminotransferase changes in Iranian people infected by parasite.
Materials and Methods: In this cross-sectional study, blood samples were collected from 183 parasite-infected patients. After serum isolation in laboratory, Alanine aminotransferase (ALT) and Aspartate aminotransferase (AST) rates of all samples were measured according to IFCC standard method, and after recording in the information form, the results were analyzed using descriptive statistics.
Results: The results of this study showed that patients were infected by 19 different types of parasites. Also, the results showed that the average value ​​of ALT and AST in patients were equal to 32.30 ±23.40 and 38.60±34.80, respectively. The ANOVA test showed remarkable statistical differences between these values ​​and various infections. There was positive and significant correlation between ALT and AST.
Conclusion: The abnormality in liver function in patients with eosinophilia can be caused by parasitic infections in endemic areas; therefore, it can be the cause of a differential diagnosis for physicians.  Generally, non-significant changes in transaminase levels can also be attributed to the infection low intensity in patients tested.

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Aims: The aim of this study was to investigate the rate of changes in liver enzymes in the plasma of Epinephelus stoliczkae under the exposure of different concentrations of potassium dichromate during 21days in vitro.
Materials & Methods:200 pieces of Epinephelus stoliczkae with average total length 29.6±2.2cm and average total weight389.5±92.4g were caught from the Oman Sea. Three treatments of 3.6, 7.31 and 14.6mg/L chromium(three replications and one control) were selected to sub-lethal toxicity test. The fish were exposed to chromium for 21 days and at 0.5, 1, 7, 14 and 21 days after the start of the experiment to measure the levels of liver enzymes aspartate aminotransferase(AST), alanine aminotransferase(ALT) and alkaline Phosphatase(ALP), blood was obtained from tail stems of fish. The amount of enzymes was measured using photometric method and values ​​were expressed inU/L.
Results: The highest and lowest levels of liver enzymes in Epinephelus stoliczkae were: aspartate aminotransferase=198.16±6.21-298±10.28, alanine aminotransferase=38±2.56-81±2.19, alkanin phosphatase=118±4.21-177±2.7U/L.Over time, the amount of liver enzymes in different treatments increased compared to the control group and showed a statistically significant difference(P<0.05).For all three liver enzymes, the highest amount was recorded in the third treatment and 21 day and the lowest in the first treatment and time of 0.5 days.
Conclusion:In this experiment,liver enzymes increased in response to an increase of chromium concentration and duration of exposure, which could be due to damage the liver cells and release of liver enzymes into the plasma.In general, liver enzymes can be used as biomarkers of pollution in natural environments.