Showing 4 results for Fucoidan
Farideh Ghalebi, Amirhossein Smiley, Abdolmohammad Abedian Kenari,
Volume 9, Issue 3 (8-2020)
Abstract
The effect of different levels of fucoidan on fatty acid profile and growth of rainbow trout were investigated. 150 fish (average weight 18.84 ± 70.7) were distributed in 15 fiberglass tanks (100 liters) and fed for 8 weeks at different levels (0 (control), 0.1%, 0.5%, 1% and 2% fucoidan). The results showed that the treatment with the highest amount of fucoidan had the highest final weight, specific growth rate and body weight gain, and there was a significant difference between treatments (p <0.05). There was no significant difference between feed conversion ratio and different treatments (p> 0.05). The difference between EPA, DHA, SFA, MUFA, n-3, HUFA and ratio of n-3 to n-6 was not significant (p >0.05), while PUFA and Arachidonic acid significantly different between treatments (p <0.05) and the highest value was observed in in treatment 2 and 1% respectively. Based on the results of this study, it can be concluded that this type of Polysaccharide at high doses (1 and 2% of fucoidan) can improve the growth performance and maintain the quality of muscle fatty acids.
Saeed Khajavi, Mehdi Tabarsa, Hassan Ahmadi Gavlighi, Masoud Rezaie,
Volume 10, Issue 1 (1-2021)
Abstract
Polysaccharides possess diverse biological properties due to complexity of chemical structure and heterogeneity of molecular weight which could be improved through engineering approaches and chemical modifications. The objective of the present study was to determine the antioxidant and anti-diabetic effects of marine and land originated polysaccharides and explore the correlation between molecular weight and biological activities. Hence, four polysaccharides with varying size distribution and average molecular weight including fucoidan and alginate from brown seaweed Padina pavonica and polysaccharides from Flixweed (Descurainia sophia) and Fennel (Foeniculum vulgare) were subjected to hydrolysis in three levels using 0.05N hydrochloric acid at 100 C for 5, 10 and 20 minutes. The average molecular weight ranged between 2059.5-3781.8 in fucoidan, 1774.4-2324.9 in alginate, 720.4-1373.8 in Flixweed and 5752.6-14077.5 × 103 g/mol in Fennel. The relation between molecular weight reduction and α-amylase activity inhibition was decreasing in fucoidan (52.1-32.8%) and alginate (67.6-32.2%) and increasing in Fennel (61.2-45.0%). Reduction of molecular weight enhanced the DPPH radical scavenging and ferric reducing power of fucoidan (47.9-27.8%; 0.47-0.37 Abs) and Fennel (39.0-12.7%; 0.34-0.16 Abs). The effect of molecular weight reduction was limited on antioxidant activities of alginate and Flixweed. Overall, the findings of the current study revealed that molecular weight is a determinant factor affecting bioactivities of the tested polysaccharides and thus their applications as ingredients having anti-diabetic and antioxidant functions could be possible in their native and/or hydrolyzed forms.
Masoumeh Ghanbari Kiasara, Mehdi Tabarsa, Hassan Ahmadi, Amin Mokhlesi,
Volume 11, Issue 4 (12-2022)
Abstract
The aim of the current study was the evaluation of stepwise recovery of fucoidan extracted from seaweed Nizamuddinia zanardinii and the assessment of relationship between sulfate content and molecular weight with its antioxidant activity. After the removal of pigments and low molecular weight compounds, fucoidan extracted with water was precipitated using different concentrations of ethanol at three levels (30, 50 and 70%). Three fractions of Fuc30, Fuc50 and Fuc70 showed molecular weights of 731.62, 655.76 and 10.41 × 103 g/mol, respectively. The content of sulfate esters in the obtained fractions were measured between 6.49-25.03%. The color evaluation of produced fucoidans by a digital chroma meter indicated the highest lightness index for Fuc50 fraction. Antioxidant results were varying in DPPH radical (43.93-89.40%) and ABTS radical (25.05-96.10%) scavenging activities as well as Fe3+ reducing power (Abs of 0.142-0.259). Overall, the findings of the present study indicated that stepwise precipitation of fucoidan from N. zanardinii leads to production of fractions with different chemical and molecular weight characteristics and antioxidant activities. Besides, although all isolated fucoidan fractions are introduced as potent antioxidant compounds, polymers possessing lower molecular weight and greater sulfate content exert higher antioxidant activities.
Mehdi Alboofetileh,
Volume 13, Issue 4 (11-2024)
Abstract
| Purpose of present study was extraction of fucoidan from Sargassum ilicifolium using hot water (HWM) and enzymatic-ultrasonic (EUM) methods and evaluation of its properties. The yield, FT-IR spectra, antioxidant (DPPH radical scavenging and reducing power) and emulsifying properties of extracted fucoidan were evaluated. Results showed that the yield of fucoidan extracted by EUM (11.49%) was higher than those extracted by HWM (9.15%). The FT-IR spectra of both polysaccharides were similar and confirmed the presence of sulphate, hydroxyl and carboxyl groups. Polysaccharides extracted by HWM method showed higher DPPH radical scavenging (36.27-49.81%) and reducing power (0.114-0.173 Abs) activities than those extracted by EUM (23.20-38.83% and 0.126-0.169 Abs). Results also showed that both of the extracted fucoidan were able to emulsify the sunflower, corn, and canola oils. In this regards, fucoidan extracted by HWM showed higher emulsification index (E24) in sunflower (34.93%) and corn oils (30.49%). However, fucoidan extracted by EUM showed higher E24 in canola oil (38.82%). The results of the present study showed that the extracted fucoidan possess biological and functional properties and therefore it can be used as an active component in the formulation of nutraceuticals supplements and functional food products. |
