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The growth performance, biomass and survival of the marine polychaete (Perinereis nuntia)reared on different sandy substrates were evaluated. For this purpose, larvae of P. nuntia with initial length of 1 cm were collected and cultured on 4 different sandy substrates for 4-month period. The tested sands were collected from Bandargah Beach (Bushehr provience) and graded by screenings to 4 substrates grain size of  <0.5, 0.5-2, 2-4 and  >4 mm with 4 replications. At the end of the experiment, the worms grown in the sandy bed of less than 0.5 mm had significantly higher final weight and specific growth rate (p<0.05) and worms grown in the sandy bed more than 4 mm had higher survival and biomass (p<0.05). In general, this study showed that using different sandy substrates had no significant effects on growth performance and survival of P.nuntia.