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Extracted polysaccharides from green seaweeds are heterogeneous in structural and molecular properties. Basically, sulfated polysaccharides from green seaweeds contain various amounts of rhamnose (16.5-45.0%), xylose (2.1-12.0%), glucose (0.5-6.4%) and sulfate (16.0-23.2%), and their building blocks are chiefly comprised of β-D-GlcpA-(1 → 4)α-L-Rhap3s. Molecular weight of sulfated polysaccharides varies from 93.4 × 103 to 1690 × 103 g/mol. The biological effects of seaweed sulfated polysaccharides are immunomodulation, cancer cell growth suppression, antioxidation, antihyperlipidemic, antiviral and anticoagulation. As the chemical structure and molecular properties of sulfated polysaccharides differ from one seaweed species to another, the biological properties varies subsequently. Overall, given the fact that highly variable marine environment can significantly incorporate into the existing discrepancies of sulfated polysaccharide structures due to seaweed phylogenetic differences, executing more comprehensive studies on various species is necessary to have a better understanding of their function and future applications

Keywords: Seaweeds, Ulvan, Functional foods, Chemical structure, Biological activity

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